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The week's question
In March 2025, in the thread "Re: OT, out", Umm asked the members: "Do you think it is because America is made up of magical soil that makes businesses based in America magically profitable?" This week it is put to everyone again. The button below opens the small thread re-asking it - read what others have said so far, then give your own answer as an ordinary reply.
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Halls of Shrewd'm / US Policy
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Author: Dope1 ⎊  😊 😞
Number: of 86277 
Subject: Re: Lincoln pool improvement recognized abroad
Date: 06/20/26 2:21 PM
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The problem with hating 24/7 is that chemically your body cranks up more cortisol. The additional cortisol starts screwing with your brain over time:

helpdementia.com - The link between cortisol imbalance and alzheimers disease

Alzheimer’s disease is a complex condition that affects millions of people worldwide, causing memory loss and cognitive decline. Recent research has highlighted a potential link between cortisol imbalance and the development of Alzheimer’s. Cortisol is a stress hormone produced by the adrenal gland, and its levels can significantly impact brain health.

Woof. Do yourselves a favor. Learn to live in peace.

Or don't:
pmc.ncbi.nlm.nih.gov: Depression and dementia: the role of cortisol and vascular brain lesions. AGES-Reykjavik Study

Results
During 8.8±3.2 years of follow-up, 843 persons developed dementia, including 397 with AD. Current MDD was associated with an increased risk of developing all-cause dementia (HR 2.17; 95% CI 1.66–2.67), with risks similar for AD and non-AD, while remitted MDD was not (HR 1.02; 95% CI 0.55–1.49). Higher levels of evening cortisol increased risk of dementia, but this was independent of MDD. WMH partially explained the relation between current MDD and dementia risk but remained increased (HR 1.71; 95% CI 1.34–2.08).

Conclusion
The current study highlights the importance of LLD in developing dementia. Higher basal cortisol levels and WMH were independently associated with increased risk of dementia. Neither the glucocorticoid cascade nor the vascular hypotheses fully explained the relation between depression and dementia.

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This community has written 86,214 posts about US Policy. The article-length ones it recommended most:
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