Donald Trump has frequently made public statements asserting that his knowledge exceeds that of domain experts, specialists, military officials, or public health professionals.
Below is a breakdown of his notable quotes claiming superior knowledge, with a focus on COVID-19 and health sciences, followed by other policy areas.

1. COVID-19 & Medical Science
"A Natural Ability" for Medical Science
During a visit to the Centers for Disease Control and Prevention (CDC) headquarters in Atlanta, President Trump claimed that the doctors at the facility were astonished by his grasp of the virus:
"I like this stuff. I really get it. People are surprised that I understand it. Every one of these doctors said, 'How do you know so much about this?' Maybe I have a natural ability. Maybe I should have done that instead of running for president."
— Press briefing at the CDC, March 6, 2020
Learning About COVID-19
While hospitalized with COVID-19 at Walter Reed National Military Medical Center, he asserted that his experience gave him an understanding superior to theoretical learning:
"I learned a lot about COVID. I learned it by really going to school... And I get it, and I understand it, and it's a very interesting thing."
— Video message from Walter Reed Medical Center, October 4, 2020
Dismissing Top Public Health Officials
During a campaign call, Trump dismissed government scientists and infectious disease experts—specifically calling out Dr. Anthony Fauci, director of the NIAID:
"People are tired of COVID. People are saying, 'Whatever. Just leave us alone.' They're tired of hearing Fauci and all these idiots... Fauci is a disaster. If I listened to him, we'd have 500,000 deaths."
— Campaign call, October 19, 2020
"Natural Instinct for Science"
Addressing his skepticism regarding climate science and environmental reports, Trump referenced his family genetics to explain his scientific understanding:
"My uncle was a great professor at MIT for many years, Dr. John Trump. And I didn't talk to him about this particular subject, but I have a natural instinct for science, and I will say that you have scientists on both sides of the picture."
— Interview with the Associated Press, October 2018

2. Military, Defense & Foreign Policy
On ISIS and Strategy:
"I know more about ISIS than the generals do. Believe me."
— Campaign rally in Fort Dodge, Iowa, November 12, 2015
On Drone Warfare:
"I know more about drones than anybody."
— Cabinet meeting at the White House, January 2, 2019
On Technology and Offense/Defense:
"I know more about offense and defense than they will ever understand... and nobody even understands it but me."
— Public remarks on defense and trade technology

3. Economy, Tax, & System Knowledge
On Taxes & Tax Law:
"I understand the tax code better than anybody that’s ever run for president."
— Debate / Campaign trail, 2016
On Renewable Energy & Wind Turbines:
"I know a lot about wind. I’ve studied it better than anybody I know."
— Speech in West Palm Beach, Florida, December 21, 2019
On Debt & Money:
"Nobody knows more about debt than I do. I’m the king of debt. I understand money better than anybody."
— Media interviews, 2016
On Campaign Finance & Politics:
"Nobody knows more about campaign finance than I do... I know more than these politicians. These guys don't know anything."
— Campaign rallies, 2015–2016