InParadise wrote: "Why not start a very need human trial in breast cancer patients while also continuing to look at the other cancers in mice? The current climate in gov't funding of science?"

Breast cancer trials are very expensive. Partly because of the cost of the drug. Partly because of the cost of following the patients for a long time because breast cancer can recur years later.

It would be hard to recruit for a controlled trial. Who would volunteer to take the chance of getting a control (no drug at all) when there are so many effective treatments? Even if the "control" was comparison with an established treatment I wouldn't agree to use a new, unproven drug.

On the other hand, pancreatic cancer has no effective treatments. It's fast-moving which would give rapid results. Patients would readily volunteer since the alternative is certain death.

This makes more sense to me.
Wendy

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