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Author: onepoorguy 🐝  😊 😞
Number: of 221 
Subject: ALZ
Date: 04/12/2024 8:14 PM
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Interesting new development.

https://www.sciencealert.com/scientists-find-gene-...

A newly discovered variant in the FN1 gene, which is responsible for making the fibronectin protein, reduces the likelihood of developing Alzheimer's by up to 70 percent. This finding could lead to more effective treatments for the disease.
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Author: sheila727   😊 😞
Number: of 221 
Subject: Re: ALZ
Date: 04/12/2024 8:24 PM
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This is the first truly exciting Alzheimer's related research that I've seen! And I wonder if this gene is involved in other brain problems as well. I wonder if too active a gene would prevent successful mitophagy and autophagy in the brain. Not being able to get rid of the garbage would become highly inflammatory.
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Author: weatherman   😊 😞
Number: of 48427 
Subject: Re: ALZ
Date: 05/12/2024 3:49 PM
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if one is aware of the critical nature payload packaging&delivery had to do with mRNA breakthroughs, try googling 'roche brain shuttle'.
it could be a critical piece in any future ALZ intervention.

this may be some further pattern forcing, but consider that despite being heavily analyzed & tracked mega caps, the GLP1 business success of novo and lilly came as a surprise to experts well aware of diabetes research.
in the same way, i see 'latent' research gems at roche in the field of neurology, further substantiated by their biogen partnership.

if not ALZ, roche is still one of the best run global revenue companies that is inexpensive by being out of the S&P500.
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